Endocrine Abstracts

Quercetin and resveratrol, powerful antioxidants and blockers of intracellular mTOR signalling system, are widely distributed in edible plants. Their action on ovarian cell functions and the interrelationships with gonadotropin are studied insufficiently. We examined the effect of FSH, quercetin, resveratrol and their combinations on proliferation and apoptosis of cultured porcine ovarian granulosa cells. Accumulation of marker of proliferation (PCNA) and marker of apoptosis (...

The aim of our studies was to examine the effect of some food, drink and medical plants and their molecules on female ovarian endocrine and other functions in vitro and in vivo. We analysed the effects of plant (green tea, rooibos, ginkgo, flaxseed, chia, yukka) extracts and plant substances (green tea polyphenols, green tea epigallocatechin-3-gallate, curcumin, resveratrol, diadzein and diosgenin) on the release of hormones and markers of proliferation, apop...

The aim of our study was to examine the influence of green tea molecules on basic ovarian functions. For this purpose we have examine the effect of green tea extract, fraction of antioxidants (GTAO) and green tea fraction of polyphenols (GTPP) (at the doses 0, 1, 10, and 100 μg/ml) on proliferation, apoptosis, and steroidogenesis by cultured porcine ovarian granulosa cells. Markers of proliferation (PCNA) and apoptosis (bax) were detected by immunocytochemistry. Secretion...